A Multi-Channel, Flex-Rigid ECoG Microelectrode Array for Visual Cortical Interfacing

A Multi-Channel, Flex-Rigid ECoG Microelectrode Array for Visual Cortical Interfacing

High-density electrocortical (ECoG) microelectrode arrays are promising signal-acquisition platforms for brain-computer interfaces envisioned, e.g., as high-performance communication solutions for paralyzed persons. We propose a multi-channel microelectrode array capable of recording ECoG field potentials with high spatial resolution. The proposed array is of a 150 mm2 total recording area; it ...

A Gate-array/multi-electrode Device: Circuit Performance and Interfacing

The Twente 128-fold 3-dimensional multimicro electrode device for endoneural stimulation is controlled by a 4x4 mm CMOS gate array chip. The chip contains the electronic circuitry, i.e. eight 16-channel multiplexers, eight double current sourca and six Merentid amplifiers. Control of the gate array circuitry by a PC is done by a PCI interface. We present (aspects of) the design and realization ...

Flexible and Flex-Rigid Circuits

Design and Fabrication of a Microelectrode Array Dedicated for Cortical Electrical Stimulation

A manufacturing process has been developed for a microelectrode array that can he used for stimulation of the visual cortex to provide an effective sense of sighf to the blind. The first prototype merges sixteen 316L stainless sfeel electrodes on a 4x4 array. Several arrays can then he assembled together in a mosaic configuration to cover a large portion of the visual area. To reduce brain inju...

Multi-well microelectrode array recordings detect neuroactivity of ToxCast compounds.

Spontaneous activity in neuronal cultures on microelectrode arrays (MEAs) is sensitive to effects of drugs, chemicals, and particles. Multi-well MEA (mwMEA) systems have increased throughput of MEAs, enabling their use for chemical screening. The present experiments examined a subset of EPA's ToxCast compounds for effects on spontaneous neuronal activity in primary cortical cultures using 48-we...